Science for All newsletter

Science for All | What is lipidomics?

A doctor holds a bag of blood plasma donated by a coronavirus survivor. File

A doctor holds a bag of blood plasma donated by a coronavirus survivor. File | Photo Credit: AP

This article forms a part of The Hindu’s Science for All newsletter, which explains all things Science, without the jargon. Subscribe here

Lipidomics is an analytical method that provides detailed insights into the fatty acid profiles in blood plasma. Fatty acids occur in the human organism mainly as part of complex molecules, called lipids. Based on their molecular structure, they are classified into numerous different lipid classes and types. The sum of all of them within an organism is called the lipidome.

Understanding the lipid metabolism plays an important role in better deciphering cardiovascular diseases and type 2 diabetes. However, little is known about the molecular relationships. Using lipidomics, a research team recently identified those lipids that are statistically associated with cardiovascular disease and type 2 diabetes. In addition, the scientists found that a diet with an increased proportion of unsaturated fatty acids (FAs) leads to a reduction in risk-associated lipids and an increase in low-risk lipids.

Cardiovascular disease is the leading cause of death worldwide, accounting for around 18 million deaths per year. People with type 2 diabetes have a two- to threefold increased risk of suffering a heart attack or stroke. Therefore, there is a need to identify biomarkers that can indicate the development of disease at an early stage in order to prevent or at least mitigate its onset. The team found about 69 lipids associated with disease risk. Using lipidomics, researchers aim to identify a lipidomics-fingerprint in the blood that depicts the effects of a test diet and check whether it is associated with long-term risk of cardiovascular disease.

(If this newsletter was forwarded to you, you can subscribe to get it directly here.)

From the Science Pages

COVID-19 surge preparedness with AI, genomic surveillance 

Why are blue straggler stars different from the norm

Generating energy from banana peel 

Question Corner

Can old skin cells be reprogrammed to make them young? Read the answer here

Flora and Fauna

Invasive species threatens wildlife habitats of Western Ghats 

When birds transition from drab to colourful 

Garbology lessons create a new generation of little waste warriors 

Kadungalloor set to launch its own rice brand 

The Hindu’s Science for All newsletters are carefully curated to help you understand everyday events as well as the wonders of the universe. Subscribe here!

Our code of editorial values

This article is closed for comments.
Please Email the Editor

Printable version | Jun 27, 2022 11:59:17 am |