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Johnson & Johnson's HIV vaccine fails mid-stage study in Africa

The study will not continue, based on the data, J&J said.   | Photo Credit: AP

Johnson & Johnson said on Tuesday its experimental vaccine failed to provide enough protection against HIV in sub-Saharan Africa to young women who are at high risk of being infected.

The mid-stage trial failure highlights the challenges of vaccine development, especially for HIV or human immuno deficiency virus, which has no approved vaccines.

"HIV is a unique and complex virus that has long posed unprecedented challenges for vaccine development because of its ability to attack, hijack and evade the human immune system," Paul Stoffels, J&J's chief scientific officer, said in a statement.

The study testing the vaccine included the participation of 2,600 women across five Southern African countries, where women and girls accounted for over 60% of all new HIV infections last year.

The trial of the vaccine, which is based on the adenovirus design which J&J's COVID-19 vaccine also uses, was supported by the National Institute of Allergy and Infectious Diseases and the Bill & Melinda Gates Foundation.

The study will not continue, based on the data, J&J said. Participants in the study will be informed about the results and told whether they received a placebo or the vaccine.

J&J said it is studying the safety and efficacy of a different composition of the vaccine regimen among homosexual men and transgender persons.


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Printable version | Oct 25, 2021 4:41:15 AM | https://www.thehindu.com/news/international/johnson-johnsons-hiv-vaccine-fails-mid-stage-study-in-africa/article36201533.ece

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