Scientists in China have bred the country’s first genetically engineered rhesus monkey, a step that could speed up the development of cures for diseases ranging from cancer to Alzheimer’s.
Scientists used green fluorescent protein (GFP), a substance originally isolated from a jellyfish and now commonly used as a biotech marker, and implanted transgenic embryos in the uteri of surrogate mother monkeys, said Ji Weizhi, a researcher with the Kunming Institute of Zoology under the Chinese Academy of Sciences.
Two transgenic monkeys -- that contained artificially planted genetic material -- were born in June 2008, both carrying the GFP gene.
An animal tagged with GFP glows green when exposed to ultraviolet light, proving that a key gene sequence has been switched on, the China Daily reported.
One of the two monkeys is still alive, making China the third country to have genetically engineered a monkey, after the US in 2001 and Japan last year.
The success could eventually lead to the cultivation of lab monkeys that can be infected with human diseases and studied, said Niu Yuyu, a member of the research team.
“The work is important because medical researchers have wanted an animal model that is closer to the human anatomy than rodents,” said Niu.
Mice that are genetically engineered to have the symptoms of certain human diseases have been the mainstay of lab work and allowed scientists to test their theories before trying them out on human volunteers.
Monkey tests, however, are controversial, as experts have warned of the potential for an ethics storm, brewed by fears that technology used on primates could be used to create genetically engineered humans.