Nineteen people were killed and six injured on Tuesday in an explosion at a medical clinic in the north of the Iranian capital Tehran, the official IRIB news agency reported, quoting state officials.
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A gas leak caused the blast, Tehran Deputy Governor Hamid Reza Goudarzi told state television.
A video posted on social media appeared to show multiple explosions at the north Tehran site and another showed firefighters using a ladder to reach the roof of the building.
A fire touched off by the blast has been extinguished, Jalal Maleki, the Tehran Fire Department spokesman said on state TV.
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The clinic, which had 25 employees inside at the time of the blast, primarily carries out light surgeries and medical imaging, Harirchi said.
Last week, an explosion occurred close to a sensitive military site near Tehran which the defence ministry said was caused by a leaking tank at a gas storage facility. No deaths or injuries were reported.