NASA’s ‘twins study’ highlights effects of spaceflight on body

It will guide future biomedical space research and help plan a safer Mars trip

Published - April 12, 2019 11:37 pm IST - Washington

Scott Kelly, right,  and his twin brother Mark Kelly .

Scott Kelly, right, and his twin brother Mark Kelly .

A NASA study of a U.S. astronaut who spent a year in space while his twin brother remained on the earth is providing insights into the effects of spaceflight on the human body, researchers said on Thursday.

U.S. astronaut Scott Kelly spent a year on the International Space Station while his identical twin Mark Kelly, also a former NASA astronaut, stayed on the ground.

The researchers who carried out the “NASA Twins Study” found that most of the changes to Mr. Scott’s body during his time in space returned to normal within months of his return to the earth — although not all of them. The findings, published in the journal Science , were encouraging to scientists and engineers envisioning interplanetary travel such as an eventual trip to Mars, a mission that could last two to three years.

Comprehensive study

“The study is the most comprehensive review of the response of the human body to spaceflight ever conducted,” said Dr Susan Bailey of Colorado State University.

Dr Steven Platts, deputy chief scientist of NASA’s Human Research Program, said it will “guide future biomedical space research and allow us to have a safer journey to and from Mars.”

Using Mr. Mark as a baseline, 84 researchers at 12 universities documented the molecular, cognitive and physiological effects of Mr. Scott’s year in space.

Mr. Scott, 50, spent 340 consecutive days on the ISS — from March 27, 2015 to March 1, 2016.

Dr Michael Snyder of Stanford University said there are “thousands of gene and molecular changes that occur as someone goes in space. Virtually all of those returned to normal (in Scott) by six months,” Mr. Snyder said.

“Our main findings in Mr. Scott were that the carotid artery wall became thicker early in flight and remained so throughout the mission,” Dr. Stuart Lee of NASA’s Johnson Space Center said.

Mr. Mark did not have any such thickening.

Mr. Scott lost 7% of his body mass during his time on the ISS, possibly due to poorer nutrition in space and a lack of exercise, while Mr. Mark gained about 4%.

In one test, flu vaccination delivered a similar immune response in them .

Cognitive tests before, during and after the flight found that Mr. Scott’s cognitive performance declined post-flight in terms of speed and accuracy.

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