Premier League leader Liverpool crashed to its first defeat of the season at home to Southampton on Saturday, while Everton enjoyed a stirring 3-2 win at West Ham United.

Liverpool came close to taking the lead in the first half at Anfield when visiting goalkeeper Artur Boruc produced a full-stretch save to keep out a Steven Gerrard free-kick.

Daniel Sturridge then had a penalty appeal turned down after tangling with Dejan Lovren, and it was Lovren who broke the deadlock in the 53rd minute with a back-post header from a left-wing corner.

Only a fine triple save from Simon Mignolet prevented Southampton from adding to its lead, but Lovren's goal proved enough to inflict a first league defeat on Liverpool since a 3-1 loss to the same side last March. Everton now trails its city rival by only a point after Romelu Lukaku scored on his debut to settle a thrilling game at Upton Park and help preserve the last unbeaten record in the division.

West Ham twice took the lead, via a deflected shot from Ravel Morrison and a Mark Noble penalty, only for Leighton Baines to level on each occasion with a pair of sensational free-kicks from 25 yards.

Noble was then sent off for a rash foul on Ross Barkley before Lukaku bravely headed home an 85th-minute winner. The results:

Chelsea 2 (Oscar 52, Mikel 84) Fulham 0;Liverpool 0 lost to Southampton 1 (Lovren 53); Newcastle 2 (Remy 10, 44) lost to Hull 3 (Brady 26, Elmohamady 48, Aluko 76); Norwich 0 lost to Aston Villa 1 (Kozak 30); West Brom 3 (Sessegnon 20, Ridgewell 76, Amalfitano 90) bt Sunderland 0; West Ham 2 (Morrison 31, Noble 76-pen) lost to Everton 3 (Baines 62, 83, Lukaku 85). — AFP

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