The State's first summit on Kawasaki Syndrome was held at Mannar, near Parumala, on Sunday. T.U. Sukumaran, national president of the Indian Academy of Paediatrics, inaugurated the summit, organised by the Chennai-based Dr. K.M. Cherian Foundation.

Dr. Sukumaran said Kawasaki Syndrome was an acute self-limiting inflammatory disease of the blood vessels, especially coronary blood vessel with unknown etiology, presented as rashes, redness of eye, mouth, lymph node enlargement, swelling of hands and coronary dilatation.

If not treated with immunoglobulin and aspirin, 20 to 24 per cent of the affected persons would develop coronary artery dilatation, eventually leading to heart attack in small children, he added.

Presiding over the inaugural function, Saji Philip, organising secretary, said Kawasaki Syndrome was first described by Tomisaku Kawasaki in Japan in 1967.

Reports published in international journals show that the prevalence of the disease has been on the rise in almost all countries since the past four decades.

According to him, the disease is more prevalent in the Asia-Pacific region. Kawasaki Syndrome is reported to be the most common cause of acquired heart disease in the U.S. and Japan.