Jaipur man develops medicine from Kadamb tree
JAIPUR: A medicinal composition for the cure of diabetes, prepared from the extracts of the commonly found Kadamb tree (Mitragyna parvifolia) leaves, has been granted patent by the Controller-General of Patents, India. The composition, containing cadambine and dihydroconchonine, two types of alkaloids found in the tree, has also received an international classification number from the World Trade Organisation (WTO).
The inventor of the medicine, Suresh Sharma of Jaipur, says it took him over 20 years and bankruptcy to develop the medicine which has successfully been tried on 1,300 patients suffering from Type II diabetes.
When taken for a period ranging from 4-10 months, one of the quninoline alkaloids in the medicine, cadambine, removed insensitivity of insulin receptors situated in adipose tissues of the muscles while the other, dihydrocinchonine, regulated the production of endogenous insulin, he said.
“The existing medicines used in the treatment of diabetes aggravated the condition of the patients by causing a flare up in this genetic disorder,” Mr.Sharma said. “This medicine works without any side effects and provides total cure in a period of 4-10 months,” he added.
According to Mr. Sharma, he could successfully treat 1,300 Type II patients so far by administering them capsules of 5 mg each for less than a year. The frequency of administration of the drug varied on the patient’s condition. In the case of new patients it is generally one tablet a month while with chronic patients it is once a week.
There is no dietary restriction during the period of treatment is except for consumption of direct sugar and sugar derivatives. The commercial production of the medicine is yet to start.
Kadamb is considered a sacred tree and worshiped by Hindus in North India. The tree, associated with the Lord Krishna legend, is found in large numbers in Bharatpur district of Rajasthan and in the adjoining Mathura and Agra districts of Uttar Pradesh.
“The tree is widespread and there would not be any dearth of the raw material for the medicine,” said Mr. Sharma, who filed a petition in the Rajasthan High Court in 2003 against cutting of Kadamb trees.