After a long time, the U.S. drone campaign in Pakistan opened a new front on Thursday with the unmanned Predators striking a compound in the Orakzai tribal agency, reportedly killing at least a dozen people.

The compound was owned by Maulana Shakirullah, a commander of the Hafiz Gul Bahadar group of the Tehreek-e-Taliban Pakistan (TTP).

Orakzai has not been pounded by drones since April 2009. It was the second drone strike in the tribal areas in two days — a compound in North Waziristan’s main town of Mir Ali bore the brunt of Wednesday’s attack.