Sasidharan describes Nayana as an ‘unusual story’, about relationships, of an unlikely friendship an elderly man and a little girl form in a hospital. This film, incidentally, will be Anupam Kher’s second outing in Malayalam films and he is not a Malayali in the film. He will essay the role of the elderly man, a retired Kashmiri IPS officer. Anikha, from Kadha Thudarunu , is the little girl. The cast includes Prakash Bare, Mia, Jagadish, Kalpana, Siddique besides others. The music is by Mohan Sithara and lyrics by Sasidharan. K. S. Chitra and Jassie Gift have sung the two songs in the film.