Bird flu has re-surfaced at Lembucherra, 45 km from here, official sources said on Thursday.
More than 2,000 ducks and others birds will be culled on Friday.
Following reports of poultry deaths in the area, blood samples were collected and examined and H5 strain of avian influenza virus was found, officials said.
Meanwhile, the State government has formed 16 rapid response teams to cull ducks and other birds in the area.
Sources said the Border Security Force was alerted so that no poultry bird could enter the Indian territory.
Tripura has a 856-km border with Bangladesh. — PTI