Third-seeded Monte Carlo winner Stanislas Wawrinka joined fellow Swiss Roger Federer on the ATP Rome Masters scrapheap after a 5-7, 6-2, 6-3 loss to German 15th seed Tommy Haas. The 36-year-old has now won both of his matches with Wawrinka, a 2008 finalist at the Foro Italico.
Rohan Bopanna and Aisam-ul-Haq Qureshi yet again failed to get past the formidable team of Bob and Mike Bryan as they lost 7-5, 6-1 to the American brothers in the doubles second round.
Ana Ivanovic handed Maria Sharapova her first loss of the spring clay season as she beat the Russian eighth seed 6-1, 6-4 to reach the quarterfinals of the WTA Italian Open.
In another match, Chinese second seed Li Na defeated Samantha Stosur 6-3, 6-1 to enter the quarterfinals.
Also on Thursday, Sania Mirza and Cara Black beat Daniela Hantuchova and Mirjana Lucic-Baroni 6-3, 6-4 in the doubles second round.
The results: ATP Rome Masters: Third round: Rafael Nadal bt Mikhail Youzhny 6-7(4), 6-2, 6-1; Grigor Dimitrov bt Tomas Berdych 6-7(3), 6-2, 6-2.
Tommy Haas bt Stanislas Wawrinka 5-7, 6-2, 6-3; Milos Raonic bt Jo-Wilfried Tsonga 7-6(5), 6-4; Jeremy Chardy bt Ivan Dodig 6-3, 6-2; Andy Murray bt Jurgen Melzer 7-6(1), 6-4.
Second round: Ernests Gulbis bt Stephane Robert 6-7(1), 6-4, 6-3; Rafael Nadal bt Gilles Simon 7-6(1), 6-7(4), 6-2. Doubles: Second round: Bob & Mike Bryan bt Rohan Bopanna & Aisam-ul-Haq Qureshi 7-5, 6-1.
WTA Italian Open: Third round : Jelena Jankovic bt Flavia Pennetta 6-2, 6-3; Zhang Shuai bt Christina McHale 6-2, 4-6, 6-2; Agnieszka Radwanska bt Francesca Schiavone 6-4, 6-1.
Carla Suarez Navarro bt Simona Halep w/o; Sara Errani bt Petra Cetkovska 6-4, 7-6(3); Li Na bt Samantha Stosur 6-3, 6-1; Ana Ivanovic bt Maria Sharapova 6-1, 6-4.
Second round: Simona Halep bt Madison Keys 5-7, 6-0, 6-1; Ana Ivanovic bt Alize Cornet 7-6(1), 7-5; Maria Sharapova bt Monica Puig 6-3, 7-5.
Doubles: Second round: Sania Mirza & Cara Black bt Daniela Hantuchova & Mirjana Lucic-Baroni 6-3, 6-4.