Diabetes `may be triggered by flu virus`

November 03, 2012 08:40 pm | Updated 08:40 pm IST - London

In diabetes, cells do not take up sugar from the blood because they have lost sensitivity to the hormone insulin.

In diabetes, cells do not take up sugar from the blood because they have lost sensitivity to the hormone insulin.

Researchers have found that the flu virus may trigger diabetes, which give us a way to prevent some forms of the disease from the discovery. In diabetes, cells do not take up sugar from the blood. This can happen because cells have lost sensitivity to the hormone insulin, which leads to type 2 diabetes. Linked to diet and lifestyle, this form of the disease is rapidly becoming more common throughout the globe. Another cause of diabetes is when the immune system destroys the pancreatic cells that produce insulin. People inherit a genetic predisposition for this condition, called type 1 diabetes, but an environmental trigger is also required for it to appear, New Scientist reported.

Since the 1970s, researchers have suspected that viruses may provide this trigger, as type 1 diabetes often sets in suddenly after an infection.

Enteroviruses and rotaviruses were both implicated; something about these infections confuses the immune system enough to make it attack the pancreas. "The great thing is that even if flu only causes a few per cent of type 1 diabetes cases, we can vaccinate and prevent flu in people who are genetically predisposed, and that can have a real impact,” Ilaria Capua, of the World Organisation for Animal Health reference lab for bird flu in Legnaro, Italy, said. There are 65,000 new cases of type 1 diabetes worldwide annually, and that figure is growing by 3 to 5 percent every year.

The link between diabetes and flu adds to growing evidence that many diseases considered non-infectious are actually caused by infection - and can therefore spread. The study has been published in the Journal of Virology.

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