U.S. Secretary of State Hillary Rodham Clinton is headed on a four-nation diplomatic tour to Central Asia and the Persian Gulf on the heels of Sunday’s unauthorized release of a trove of sensitive State Department documents chronicling the behind-the-scenes conduct of U.S. foreign relations.

Ms. Clinton’s trip, announced by State Department spokesman P.J. Crowley on Sunday evening, had been planned long before hundreds of thousands of diplomatic cables were released by WikiLeaks, the online anti-secrecy group, and published by The New York Times and newspapers in Europe.

Mr. Crowley said Ms. Clinton will begin her trip on Tuesday in Kazakhstan, where she will head the U.S. delegation to a summit meeting of the Organization for Security and Cooperation in Europe, the first top—level meeting of the 56-nation group in 11 years.

Ms. Clinton also will meet with Kazakh President Nursultan Nazarbayev and his Foreign Minister, Kanat Suadabeyev. Mr. Nazarbayev has ruled Kazakhstan unchallenged since the late 1980s, when it was still part of the Soviet Union, and has been repeatedly re-elected by landslide victories.

Ms. Clinton also will visit Kyrgyzstan, which hosts a U.S. air base that is important for resupplying and ferrying U.S. troops in Afghanistan. She also will visit Uzbekistan and stop in the Persian Gulf nation of Bahrain, which hosts the U.S. Navy’s 5th Fleet headquarters.

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